Today Shawn Blanc released OopsieFocus, a script which solves the problem of hitting the OmniFocus quick entry keyboard shortcut only to discover that OmniFocus wasn’t running (and thus, nothing happened).

One alternative if you’re an Alfred user¹ is to setup a custom search that allows one to add OmniFocus tasks directly from the Alfred input window. I have mine setup with the keyword “omni”, so when I want to add a task I hit the Alfred key, type “omni Some task goes here” and I’ll have a new task in my inbox with the title of “Some task goes here”.